Dynamic processes in biology are often controlled by multiple parameters that interact in a complex nonlinear fashion. Increasingly, evidence has accumulated that such behavior exhibits the property of sensitivity to initial conditions, a feature exhibited by chaotic systems. One such system is the vasculature. In this report, we present what we believe is the first experimental demonstration ever of imaging chaotic behavior of the vasculature in a large tissue structure (i.e., the human forearm). Supporting these findings are results from numerical simulation demonstrating our ability to image and correctly characterize complex dynamic behavior in dense scattering media that experience spatiotemporally coincident variations in hemodynamic states.