Diagnostic imaging with light, and beyond

Randall L. Barbour and Harry L. Graber (1997)


In this report we consider the merits of optical methods for use as a nonionizing diagnostic imaging tool in relation to current imaging methods, and discuss critical issues needing further development. Of added promise is the potential for developing a range of optical contrast agents sensitive to different metabolic states, and for extending the utility of optical methods beyond diagnosis to create new strategies for rational therapeutic intervention.